Sea anemone genome reveals ancestral eumetazoan gene repertoire and genomic organization.
نویسندگان
چکیده
Sea anemones are seemingly primitive animals that, along with corals, jellyfish, and hydras, constitute the oldest eumetazoan phylum, the Cnidaria. Here, we report a comparative analysis of the draft genome of an emerging cnidarian model, the starlet sea anemone Nematostella vectensis. The sea anemone genome is complex, with a gene repertoire, exon-intron structure, and large-scale gene linkage more similar to vertebrates than to flies or nematodes, implying that the genome of the eumetazoan ancestor was similarly complex. Nearly one-fifth of the inferred genes of the ancestor are eumetazoan novelties, which are enriched for animal functions like cell signaling, adhesion, and synaptic transmission. Analysis of diverse pathways suggests that these gene "inventions" along the lineage leading to animals were likely already well integrated with preexisting eukaryotic genes in the eumetazoan progenitor.
منابع مشابه
Nicholas H . Putnam Repertoire and Genomic Organization Sea Anemone Genome Reveals Ancestral Eumetazoan Gene
, 86 (2007); 317 Science et al. Nicholas H. Putnam Repertoire and Genomic Organization Sea Anemone Genome Reveals Ancestral Eumetazoan Gene This copy is for your personal, non-commercial use only. clicking here. colleagues, clients, or customers by , you can order high-quality copies for your If you wish to distribute this article to others here. following the guidelines can be obtained by Per...
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ورودعنوان ژورنال:
- Science
دوره 317 5834 شماره
صفحات -
تاریخ انتشار 2007