Magnetization Transfer in Cardiac Truefisp Imaging
نویسنده
چکیده
Session IX: Friday, February 2, 2007 307. MAGNETIZATION TRANSFER IN CARDIAC TRUEFISP IMAGING Oliver M. Weber, PhD, Klaus Scheffler, PhD, Oliver Bieri, PhD. University of Basel, Switzerland, Basel, Switzerland. Introduction: Recently, we showed that the rapid succession of high flip angle RF pulses in conventional balanced steady state free precession (bSSFP) sequences causes an on-resonancemagnetization transfer (MT) effect, resulting in signal attenuation in FIG. 1. MTR in dependence of a) flip angle (TRstrongMT = 2.9 ms; TRweakMT = 4.4 ms) and b) TRweakMT (flip angle = 45◦, TRstrongMT = 2.9 ms). Circles: measured points; line: exponential fit. c) MTR map of a LV short axis view. tissue with bound macromolecules (1). The degree of the MT effect depends on the deposited power of the RF pulse train. Variation of the RF power thus results in different MT weighting and can be used to quantify the MT effect. We applied this principle to calculate MT ratios (MTR) in myocardial tissue. Materials and Methods: A cardiac bSSFP sequence with adjustable TR was implemented on a 1.5 T MR imager (Avanto; Siemens Medical Solutions) to assess MT variation in myocardial tissue. Short axis views of the left ventricle (LV) were acquired in a normal volunteer.A single phasewas acquired using a
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