Primary cutaneous marginal zone lymphoma with leptomeningeal involvement and a durable response to rituximab
نویسندگان
چکیده
CNS: central nervous system CSF: cerebrospinal fluid PCMZL: primary cutaneous marginal zone lymphoma WBC: white blood cells BACKGROUND Primary cutaneous marginal zone lymphoma (PCMZL) is an indolent B-cell lymphoma, typically characterized by frequent cutaneous recurrences and rare systemic involvement. Lymph nodes, bone, and bone marrow are commonly affected sites in rare cases of extracutaneous disease. Secondary involvement of central nervous system (CNS) in confirmed PCMZL is unreported.
منابع مشابه
[Splenic marginal zone B-cell lymphoma with epidermotropic skin involvement].
Marginal zone B-cell lymphoma (MZL) is subclassified into extranodal MZL of mucosa-associated lymphoid tissue (including cutaneous lymphomas), splenic MZL, and nodal MZL. We report the case of a 68-year-old man with erythematous-violaceous plaques and nodules. Skin biopsy showed an epidermotropic lymphocytic infiltration and cytology and immunohistochemistry were consistent with MZL. The workup...
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