Author’s response to reviews Title: A review of the experimental evidence on the toxicokinetics of carbon monoxide: The potential role of pathophysiology among susceptible groups Authors: Prabjit Barn ([email protected])

Title: A review of the experimental evidence on the toxicokinetics of carbon monoxide: The potential role of pathophysiology among susceptible groups Authors: Prabjit Barn ([email protected]) Luisa Giles ([email protected]) Marie-Eve Héroux ([email protected]) Tom Kosatsky ([email protected]) Version: 1 Date: 25 Dec 2017 Author’s response to reviews: We thank the reviewers for their valuable comments, which we have attempted to address in the responses below. We would also like to draw the editor’s attention to our revised manuscript title. We believe that the revised title more accurately represents our review. Original title: A review of experimental evidence on carbon monoxide and health: Does pathophysiology increase susceptibility in persons other than those with cardiovascular disease? Revised title: A review of the experimental evidence on the toxicokinetics of carbon monoxide: The potential role of pathophysiology among susceptible groups