Invited Review Methods for detection of reactive metabolites of oxygen and nitrogen: in vitro and in vivo considerations
نویسندگان
چکیده
Margaret M. Tarpey, David A. Wink, and Matthew B. Grisham Department of Anesthesiology and the Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, Alabama 35294; Radiation Biology Branch, National Cancer Institute, Bethesda, Maryland 20814; and Department of Molecular and Cellular Physiology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130
منابع مشابه
Methods for detection of reactive metabolites of oxygen and nitrogen: in vitro and in vivo considerations.
Facile detection of reactive oxygen and nitrogen species in biologic systems is often problematic. This is a result of the numerous cellular mechanisms, both enzymatic and nonenzymatic involved in their catabolism/decomposition, the complex and overlapping nature of their reactivities, as well as the often limited intracellular access of detector systems. This review describes approaches to the...
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