Safety advantages of topical versus oral nonsteroidal antiinflammatory drugs.
نویسنده
چکیده
منابع مشابه
Randomized double-blind trial comparing oral paracetamol and oral nonsteroidal antiinflammatory drugs for treating pain after musculoskeletal injury.
STUDY OBJECTIVE We investigate the efficacy and safety of oral paracetamol compared with oral nonsteroidal antiinflammatory drugs or combination therapy in relieving pain after blunt limb injury in an emergency department (ED). METHODS This was a double-blind, randomized, controlled study in an ED of a university hospital in the New Territories of Hong Kong. Three hundred adult patients with ...
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Nonsteroidal antiinflammatory drugs have been widely used for the management of inflammation, pain and nociception. Gastric intolerance caused by most of the nonsteroidal antiinflammatory drugs used today restricts their use. Several approaches have been proposed to modify the parent nonsteroidal antiinflammatory drugs molecule in order to reduce their gastric toxicity. Oral prodrug approach is...
متن کاملTopical Nonsteroidal Anti-Inflammatory Drugs for Chronic Musculoskeletal Pain in Adults.
OBJECTIVE To assess the efficacy and safety of different topically applied nonsteroidal anti-inflammatory drugs (NSAIDs) compared with oral NSAIDs and with a placebo in the treatment of chronic musculoskeletal pain.
متن کاملA Nonsteroidal Antiinflammatory Drug: Aceclofenac
Aceclofenac (AC) is an effective non-steroidal antiinflammatory drug, which possesses remarkable antiinflammatory, analgesic and antipyretic properties. The analgesic and anti-inflammatory efficacy of AC is generally equivalent to that of comparator nonsteroidal antiinflammatory drugs (NSAIDs) with similar onset of action. AC also shows stimulatory effects on glycosaminoglycan synthesis in huma...
متن کاملOral versus topical NSAIDs in rheumatic diseases: a comparison.
Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly prescribed drugs worldwide and are responsible for approximately one-quarter of all adverse drug reaction reports. NSAIDs are widely prescribed for patients with rheumatic disease--a population at increased risk for serious gastrointestinal (GI) complications. Topical administration of NSAIDs offers the advantage of local...
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ورودعنوان ژورنال:
- The Journal of rheumatology
دوره 38 3 شماره
صفحات -
تاریخ انتشار 2011