EPR Dosimetry of Chernobyl Liquidators

نویسنده

  • Vadim CHUMAK
چکیده

The paper is devoted to review of development and application of EPR dosimetry with teeth in Ukraine. It deals with specific features of the EPR dosimetry protocol, which was developed and is practically used in SCRM for retrospective dosimetry of clean-up workers (liquidators). Extensive methodological research was conducted in SCRM in order to develop an original version of EPR dosimetric protocol as well as to investigate the effects caused by confounding factors and develop approaches to their account and mitigation. The proposed EPR dosimetric protocol addresses the demand for high accuracy and reproducibility, low sensitivity threshold as well as high throughput of the technique. High qualities of SCRM version of EPR protocol were proven in the course of elaborate quality assurance program, which included a series of international intercomparisons. Creation and continuous operation of the nationwide tooth acquisition network is another key to the success of EPR dosimetry in Ukraine. Particular attention in the paper is paid to definition of the most optimal way of application of EPR dosimetry for dosimetric support of the post-Chernobyl medical follow-up. The main applications of EPR dosimetry in Ukraine are both routine high precision reconstruction of doses to Chernobyl clean-up workers and the use of EPR dose estimates as a reference dose for validation of other retrospective dosimetry techniques. The latter proved to be the most efficient application of EPR dosimetry in the post-Chernobyl situation. EPR dosimetry was used for testing such methods of retrospective dosimetry as FISH, ADR, SEAD and RADRUE. Nowadays EPR dosimetry plays inevitable role in dosimetric support of the post-Chernobyl medical follow-up studies. Introduction The Chernobyl accident and obvious failure of routine dosimetric monitoring of clean-up workers (liquidators) had stimulated significant development of various methods of retrospective dosimetry. Among those methods one of the most adequate proved to be an EPR dosimetry with teeth. Over last decade EPR dosimetry made all way from unique experimental technique to the tool of routine dose reconstruction. Many different applications are known for EPR dosimetry with teeth. It was used for determination of doses received in course of radiotherapy [1], dose reconstruction for atomic workers [2] as well as in several cases of accidental exposure [3-7]. In recent years, several review papers [8-11] and one book [12] were published dealing with various aspects of EPR dosimetry. Notable role in the process of development and implementation of this method belongs to the research performed in Scientific Center for Radiation Medicine (SCRM) AMS Ukraine, in particular to the work performed in collaboration with leading laboratories worldwide [8, 13-21]. This paper is dealing with some specific features of the EPR dosimetry protocol which was developed and is practically used in SCRM, briefly touches results of investigations performed in this institute, and concentrates to a larger extent on practical applications, which EPR dosimetry had found in Ukraine. Particular attention in the paper is paid to definition of the most optimal way of application of EPR dosimetry for dosimetric support of the post-Chernobyl medical follow-up.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A transferability study of the EPR-tooth-dosimetry technique.

The transferability of a measurement protocol from one laboratory to another is an important feature of any mature, standardised protocol. The electron paramagnetic resonance (EPR)-tooth dosimetry technique that was developed in Scientific Center for Radiation Medicine, AMS, Ukraine (SCRM) for routine dosimetry of Chernobyl liquidators has demonstrated consistent results in several inter-labora...

متن کامل

ret/PTC1 and ret/PTC3 in thyroid tumors from Chernobyl liquidators: comparison with sporadic tumors from Ukrainian and French patients.

Like children exposed to Chernobyl fallout, the workers who cleaned up after the accident, also known as liquidators, have exhibited an increased incidence of thyroid cancer. A high prevalence of ret/PTC3 rearrangement has been found in pediatric post-Chernobyl thyroid tumors, but this feature has not been investigated in liquidator thyroid tumors. In this study we analyzed the prevalence of re...

متن کامل

Benign Thyroid Diseases among Chernobyl Liquidators.

Seventeen years have passed since the accident at the Chernobyl Nuclear Power Plant. The only clear evidence of the result of this accident is that a dramatic increase of thyroid cancer has been observed after the accident among residents who were exposed by radiation-fallout at a young age [1]. However, the radiation risk for adults around Chernobyl remains unclear. Besides such effects among ...

متن کامل

Summation of the International Conference on Radiation and Health: radiobiology viewpoint.

The idea to hold an international conference on radiation and health arose as a natural response to the mounting evidence of serious health effects on populations resulting from the Chernobyl accident. The nature of the Chernobyl accident, where large amounts of radioactive nuclides spread in the reactor area and all over Europe, dictated the emphasis of the presented papers covering both direc...

متن کامل

Radiation-epidemiological analysis of incidence of non-cancer diseases among the Chernobyl liquidators.

The work is concerned with assessment of radiation risks for non-cancer disease among the Chernobyl liquidators from 1986 to 1996. As of 1 January 1999, the Russian National Medical and Dosimetric Registry contains medical and dosimetric data for 174,000 liquidators. The cohort of 68,309 liquidators for whom best verified medical data are available is discussed. The dose dependency of incidence...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2002