Cell-free and intracellular nucleic acids: new non-invasive biomarkers to explore male infertility

نویسندگان

  • Anne Boissière
  • Anna Gala
  • Alice Ferrières-Hoa
  • Tiffany Mullet
  • Solenne Baillet
  • Amaël Petiton
  • Antoine Torre
  • Samir Hamamah
چکیده

Male infertility is a devastating problem that affects many couples worldwide. However, the molecular mechanisms and causes of idiopathic male infertility remain unclear. Circulating cell-free nucleic acids have an important role in human physiology and emerging evidence suggests that they play a role in male infertility. This review summarizes recent results on cell-free and intracellular nucleic acids in male infertility and discusses their potential use as biomarkers of male infertility in the clinical practice.

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عنوان ژورنال:

دوره 27  شماره 

صفحات  -

تاریخ انتشار 2017