The role of PXR in 2-AAF-mediated induction of drug transport and metabolizing enzymes in mice
نویسندگان
چکیده
225 words Introduction – 370 words Discussion – 1521 words Abbreviations: PXR, pregnane X receptor; MRP, multidrug resistance-associated protein; RTPCR, reverse transcription-polymerase chain reaction; OATP, organic anion transporting peptide; 2-AAF, 2-acetylaminofluorene; BCRP, breast cancer resistance protein; CYP, cytochrome p450; ABC, ATP-binding cassette transporter; TCDD, 2,3,7,8-tetrachlorodibenzo-pdioxin; 3-MC, 3-methylcholantrene; AhR, aryl hydrocarbon receptor. This article has not been copyedited and formatted. The final version may differ from this version. DMD Fast Forward. Published on December 28, 2005 as DOI: 10.1124/dmd.105.006197 at A PE T Jornals on A uust 7, 2017 dm d.aspurnals.org D ow nladed from
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The role of pregnane X receptor in 2-acetylaminofluorene-mediated induction of drug transport and -metabolizing enzymes in mice.
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