Continuous flow coupling and decarboxylation reactions promoted by copper tubing.
نویسندگان
چکیده
A convenient and efficient flow method for Ullmann condensations, Sonogashira couplings, and decarboxylation reactions using a commercially available copper tube flow reactor (CTFR) is described. The heated CTFR effects these transformations without added metals (e.g., Pd), ligands, or reagents, and in greater than 90% yield in most cases examined.
منابع مشابه
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ورودعنوان ژورنال:
- Organic letters
دوره 13 2 شماره
صفحات -
تاریخ انتشار 2011