TRANSLATIONAL PHYSIOLOGY Cardioprotective effects of nitroparacetamol and paracetamol in acute phase of myocardial infarction in experimental rats
نویسندگان
چکیده
Yi Zhun Zhu, Chew Lan Chong, Shin Chet Chuah, Shan Hong Huang, Huey Shan Nai, How Teng Tong, Matt Whiteman, and Philip K. Moore National University of Singapore Cardiovascular Biology Research Group and Department of Pharmacology, National University of Singapore; Department of Pharmacology, School of Pharmacy, Fudan University; Emergency Department, National University Hospital; and Department of Biochemistry, National University of Singapore, Singapore
منابع مشابه
Cardioprotective effects of nitroparacetamol and paracetamol in acute phase of myocardial infarction in experimental rats.
We aimed to determine whether nitroparacetamol (NO-paracetamol) and paracetamol exhibit cardioprotective effects. Myocardial infarction (MI) was induced in rats, and drug treatment was started 1 wk before surgery. Mortality rate and infarct size at 2 days after MI were compared. Treatment groups included vehicle (saline), paracetamol (5 mg x kg(-1) x day(-1)) and NO-paracetamol (15 mg x kg(-1) ...
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