The stereoselective formation of bicyclic enamines with bridgehead unsaturation via tandem C-H bond activation/alkenylation/electrocyclization.
نویسندگان
چکیده
Bridgehead bicyclic unsaturated enamines were prepared by a tandem rhodium-catalyzed C-H bondactivation/alkenylation/electrocyclization of alkyne-tethered unsaturated imines. These strained bicyclic enamines exhibitunique reactivity: for example, they give N-Alkylated products upon treatment with alkylating reagents and undergo doublebond isomerization to alleviate ring strain upon reduction.
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ورودعنوان ژورنال:
- Journal of the American Chemical Society
دوره 130 8 شماره
صفحات -
تاریخ انتشار 2008