Catalytic asymmetric conjugate boration of α,β-unsaturated sulfones.
نویسندگان
چکیده
The α,β-unsaturated sulfones are suitable activated olefins in catalytic asymmetric conjugate β-boration. These substrates undergo smooth conjugate addition of bis(pinacolato)diboron [B(2)(pin)(2)] catalyzed by nonracemic Cu(I)-diphosphine complexes to provide, upon subsequent oxidation, β-hydroxy sulfones in good yields and high enantiocontrol.
منابع مشابه
Asymmetric metal free β-boration of α,β-unsaturated imines assisted by (S)-MeBoPhoz.
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ورودعنوان ژورنال:
- Chemical communications
دوره 47 23 شماره
صفحات -
تاریخ انتشار 2011