7122 In vivo high resolution , undistorted diffusion weighted imaging using DSDE - TFE
نویسندگان
چکیده
Purpose: to explore DSDE-TFE for in vivo high resolution, undistorted DWI and ADC calculation. Background: Diffusion weighted MRI is commonly performed using a single shot spin echo EPI acquisition. EPI techniques, however, are very sensitive to B0 inhomogeneities due to susceptibility differences. This causes geometrical distortions.Because of the high sensitivity to motion, DW-EPI is mostly constrained to single shot MRI which limits the resolution. Diffusion Sensitized Driven Equilibrium (DSDE) has been proposed to overcome these limitations [1, 2]. This method is based on a diffusion preparation that restores diffusion weighted magnetization along the longitudinal axis which can be followed by an acquisition method of choice. This allows readout strategies which are less sensitive to distortion artifacts and allow for high resolution imaging.
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