Acquired angioedema responding to rituximab.
نویسندگان
چکیده
منابع مشابه
Rituximab therapy in a patient with low grade B-cell lymphoproliferative disease and concomitant acquired angioedema
Acquired angioedema is often associated with significant morbidity. An underlying lymphatic malignancy, autoimmune disorder, adenocarcinoma, or other malignancy may be present. Screening for these disorders should occur in all patients with acquired angioedema as treatment may result in resolution of angioedema.
متن کاملA case of acquired angioedema associated with Waldenstrom’s macroglobulinemia treated with rituximab
Case presentation We report a case of Waldenstrom ́s macroglobulinemia causing an acquired deficiency of C1 esterase inhibitor in a 40-year-old woman. She initially presented with an episode of angioedema followed by many episodes of abdominal distention associated with pain, vomiting, and diarrhea for 1.5 years. Work-up revealed low C1 esterase inhibitor levels, normal C3, and nonexistent C4. A...
متن کاملA nationwide study of acquired C1-inhibitor deficiency in France
Acquired angioedema (AAE) due to C1-inhibitor (C1INH) deficiency is rare. Treatment options for acute attacks are variable and used off-label. Successful treatment of the associated lymphoma with rituximab seems to prevent acute attacks in subjects with AAE. The aim of this study was to describe AAE manifestations, its associated diseases, and patients' responses to treatments in a representati...
متن کاملRefractory Angioedema in a Patient with Systemic Lupus Erythematosus
Angioedema secondary to C1 inhibitor deficiency has been rarely reported to be associated with systemic lupus erythematosus. A genetic defect of C1 inhibitor produces hereditary angioedema, which is usually presented with cutaneous painless edema, but edema of the genital area, gastrointestinal and laryngeal tracts have also been reported.In lupus patients, angioedema may be the result of an ac...
متن کاملAcquired angioedema: a new target for rituximab?
Acquired angioedema (AAE) is a rare disorder characterized by recurrent attacks, late onset of symptoms and a marked decrease of C1 levels. Pathogenetically it is caused by an accelerated consumption of C1-inhibitor (C1-INH), resulting in C1-INH deficiency and uncontrolled complement activation. We describe successful treatment of a patient with AEE due to C1-INH autoantibody, administering 4 w...
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ورودعنوان ژورنال:
- Acta dermato-venereologica
دوره 91 6 شماره
صفحات -
تاریخ انتشار 2011