Instrumentation and calibration protocol for imaging dynamic features in dense-scattering media by optical tomography.
نویسندگان
چکیده
Instrumentation is described that is suitable for acquiring multisource, multidetector, time-series optical data at high sampling rates (up to 150 Hz) from tissues having arbitrary geometries. The design rationale, calibration protocol, and measured performance features are given for both a currently used, CCD-camera-based instrument and a new silicon-photodiode-based system under construction. Also shown are representative images that we reconstructed from data acquired in laboratory studies using the described CCD-based instrument.
منابع مشابه
An iterative method to estimate x-ray attenuation coefficients in computed tomography
Introduction: The basis of image formation in Computed Tomography (CT) lies in the x-ray linear attenuation coefficient of the scanned material. Compton scattering and photoelectric effect are the dominant interactions of the x-ray photons with the subject, in the range of diagnostic radiology. These two coefficients are important in tissue characterization by Dual-Energy CT (D...
متن کاملIterative total least-squares image reconstruction algorithm for optical tomography by the conjugate gradient method.
We present an iterative total least-squares algorithm for computing images of the interior structure of highly scattering media by using the conjugate gradient method. For imaging the dense scattering media in optical tomography, a perturbation approach has been described previously [Y. Wang et al., Proc. SPIE 1641, 58 (1992); R. L. Barbour et al., in Medical Optical Tomography: Functional Imag...
متن کاملDevelopment of an Advanced Optical Coherence Tomography System for Radiation Dosimetry
Introduction: According to the literature, optical coherence tomography (OCT) can be used measure radiation absorbed dose. This study was carried out to design a computed tomography system for the calculation of absorbed dose and optimization of dose delivery in radiotherapy using gel dosimeters. Material and Methods: An advanced charge-coupled device based OCT system was developed in laborator...
متن کاملDesign and implementation of a multifrequency near-infrared diffuse optical tomography system.
The design and implementation of a multifrequency and multispectral diffuse optical tomography system is described. Four wavelengths are utilized: 665, 785, 808, and 830 nm. The system is based on a network analyzer, which provides rf modulation signals for the laser diodes, as well as measures the amplitude and the phase of the detected signals. Six different modulation frequencies ranging fro...
متن کاملOptical tomographic imaging of dynamic features of dense-scattering media.
Methods used in optical tomography have thus far proven to produce images of complex target media (e.g., tissue) having, at best, relatively modest spatial resolution. This presents a challenge in differentiating artifact from true features. Further complicating such efforts is the expectation that the optical properties of tissue for any individual are largely unknown and are likely to be quit...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Applied optics
دوره 39 34 شماره
صفحات -
تاریخ انتشار 2000