PRRS Virus-Induced Damage to Intravascular Macrophages
نویسنده
چکیده
and Implications The results of this research suggest: (1) PRRSV has a detrimental effect on the uptake of copper particles by pulmonary intravascular macrophages (PIMs), (2) the severity of PRRSV-induced damage to PIMs differs among PRRSV isolates, and (3) PRRSV-induced decreased pulmonary clearance supports the hypothesis that PRRSV infection makes pigs more susceptible to bacterial septicemia.
منابع مشابه
In vivo replication of porcine reproductive and respiratory syndrome virus in swine alveolar macrophages and change in the cell population in bronchoalveolar lavage fluid after infection.
Replication of porcine reproductive and respiratory syndrome (PRRS) virus in swine alveolar macrophages (AM) and cell population in broncho-alveolar lavage fluid (BALF) obtained from PRRS virus-infected pigs were investigated. BALF samples were periodically collected from 6 pigs infected with PRRS virus and 3 non-inoculated control pigs by means of fiber-optic bronchoscope between post-inoculat...
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