Title:chemotherapy Induces Notch1-dependent Mrp1 Up-regulation, Inhibition of Which Sensitizes Breast Cancer Cells to Chemotherapy
نویسندگان
چکیده
Baek Kim ([email protected]) Sam Stephen ([email protected]) Andrew Hanby ([email protected]) Kieran Horgan ([email protected]) Sarah Perry ([email protected]) Julie Richardson ([email protected]) Elizabeth Roundhill ([email protected]) Elizabeth Valleley ([email protected]) Eldo Verghese ([email protected]) Beth Williams ([email protected]) James Thorne ([email protected]) Thomas Hughes ([email protected])
منابع مشابه
miR-145 sensitizes breast cancer to doxorubicin by targeting multidrug resistance-associated protein-1
Multidrug resistance-associated protein 1 (MRP1) is an important efflux transporter and overexpression of MRP1 usually leads to chemoresistance in breast cancer. Here, we found MRP1 overexpressed in human breast cancer tissues and breast cancer cell lines (compared with normal breast tissues and cell line, respectively). And MRP1 level increased in doxorubicin resistant MCF-7 cells compared wit...
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