Correction: Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis (doi: 10.1242/dmm.030114)
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Correction: Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis (doi: 10.1242/dmm.030114) Gavin Tjin, Eric S. White, Alen Faiz, Delphine Sicard, Daniel J. Tschumperlin, Annabelle Mahar, Eleanor P. W. Kable and Janette K. Burgess An error was published in Dis. Model. Mech. (2017). 10, 1301-1312 (doi: 10.1242/dmm.030114). A reference was incorrectly cited in the Results section (subsection ‘Inhibition of LO activity reduced TGF-β-induced collagen remodelling in collagen I hydrogels’). The corrected sentence and reference are below. ‘To confirm the role of LO enzymes in fibrillar collagen remodelling, 3D in vitro cell culture experiments using inhibitors of LO activity were performed. β-APN is a non-selective inhibitor of LO activity, whereas Compound A is a specific inhibitor of LOXL2 activity, referred to as PXS-S2A in a recent publication by Chang et al. (2017).’ Chang, J., Lucas,M. C., Leonte, L. E., Garcia-Montolio, M., Singh, L. B., Findlay, A. D., Deodhar, M., Foot, J. S., Jarolimek,W., Timpson, P. et al. (2017). Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer.Oncotarget 8, 26066-26078. http://doi.org/10. 18632/oncotarget.15257. The authors apologise to readers for this error.
منابع مشابه
Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive scarring disease of the lung with few effective therapeutic options. Structural remodelling of the extracellular matrix [i.e. collagen cross-linking mediated by the lysyl oxidase (LO) family of enzymes (LOX, LOXL1-4)] might contribute to disease pathogenesis and represent a therapeutic target. This study aimed to further our understanding of ...
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