Enantioselective synthesis of (+)-cephalostatin 1.
نویسندگان
چکیده
This Article describes an enantioselective synthesis of cephalostatin 1. Key steps of this synthesis are a unique methyl group selective allylic oxidation, directed C-H hydroxylation of a sterol at C12, Au(I)-catalyzed 5-endo-dig cyclization, and a kinetic spiroketalization.
منابع مشابه
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ورودعنوان ژورنال:
- Journal of the American Chemical Society
دوره 132 1 شماره
صفحات -
تاریخ انتشار 2010