A deathly DNase activity for dicer.
نویسندگان
چکیده
Recently reporting in Science, Nakagawa et al. describe an unexpected role for Dicer in chromosome fragmentation during apoptosis in C. elegans. They find that cleavage of DCR-1 by the caspase CED-3 redirects its regulatory activity, by destroying its dsRNase activity while activating an intrinsic DNase activity.
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ورودعنوان ژورنال:
- Developmental cell
دوره 18 5 شماره
صفحات -
تاریخ انتشار 2010