Plasma asymmetric dimethylarginine (ADMA) is associated with retinopathy in type 2 diabetes.

Plasma Asymmetric Dimethylarginine (ADMA) is Associated with Retinopathy in Type 2 Diabetes Mellitus

Diabetic Retinopathy Is Associated With Elevated Serum Asymmetric and Symmetric Dimethylarginines

OBJECTIVE Asymmetric dimethylarginine (ADMA), symmetric dimethylarginine (SDMA), and l-arginine directly influence nitric oxide production. Our objective was to test whether serum ADMA, SDMA, or l-arginine levels correlate with diabetic retinopathy subtype or severity. RESEARCH DESIGN AND METHODS A total of 162 subjects with type 1 diabetes and 343 with type 2 diabetes, of whom 329 subjects h...

Renal Function but Not Asymmetric Dimethylarginine Is Independently Associated with Retinopathy in Type 2 Diabetes

Background. Asymmetric dimethylarginine (ADMA) is associated with macrovascular disease and possibly with microangiopathy in type 2 diabetes (T2DM). We tested the hypothesis that ADMA is related to diabetic retinopathy (DR) independently of macrovascular disease. Methods. This cross-sectional study included 127 T2DM patients selected to achieve equal distributions of patients with and without m...

Elevated plasma asymmetric dimethylarginine as a marker of cardiovascular morbidity in early diabetic nephropathy in type 1 diabetes.

OBJECTIVE Increased plasma concentration of asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, has been associated with endothelial dysfunction, insulin resistance, and atherosclerosis in nondiabetic populations. In end-stage renal failure, circulating ADMA is elevated and a strong predictor of cardiovascular outcome. This study investigated the relation betwe...

Is There a Correlation Between Plasma Levels of Asymmetric Dimethylarginine (ADMA) Levels and Atherosclerosis in Type 2 Diabetes Patients in Turkey?

Date of acceptance / Kabul tarihi: December 5, 2016 / 5 Aralık 2016 ABSTRACT: Is there a correlation between plasma levels of asymmetric dimethylarginine (ADMA) levels and atherosclerosis in type 2 diabetes patients in Turkey? Objective: Atherosclerosis is very common in patients with diabetes mellitus (DM). We aimed to investigate the relationship between asymmetric dimethylarginine (ADMA) whi...