Alveolar Macrophages by Toll-Like Receptor Inhibition of IL-10 Receptor Function in
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منابع مشابه
Inhibition of IL-10 receptor function in alveolar macrophages by Toll-like receptor agonists.
Despite an immunosuppressive lung environment, alveolar macrophages (AM) retain the capacity to respond to microorganisms. This report demonstrates that IL-10, constitutively produced by normal alveolar epithelium, stimulates signal transduction through the IL-10R on AM and that IL-10R function can be inhibited by stimulation of Toll-like receptor (TLR) on AM. IL-10 mRNA and protein were consti...
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