Dicumarol therapy controlled by the stabilized thrombin method for determination of prothrombin.

THE RELATIONSHIP OF PLASMA PROTHROMBIN CONCENTRATiON AND THE DEGRADATION RATE OF SERUM “PROTHROMBIN- CONVERTING FACTOR” DURING DICUMAROL THERAPY

on fibrinogen and oxalated plasma revealed that serum obtained from recently coagulated whole blood contains a factor which causes conversion of prothrombin to thrombin.” 2 Since fibrinogen could not be converted to fibrin in any significant degree by addition of fresh serum, and since the rapidity of coagulation of oxalated plasma by the serum factor was proportional to the prothrombin concent...

The Comparative Action of Dicumarol and of Phenylindanedione on the Coagulase Reacting Factor and on Prothrombin *

Recent studies' have established the presence of a factor ("activator," Coagulase-reacting factor, or CRF) in plasma which is required for the coagulation of blood by staphylocoagulase. Maximum CRF activity resides in the globulin fractions of plasma, and separation from prothrombin is best achieved by repeated Seitz filtration.10 The filtration involves different rates of adsorption of prothro...

The relationship of plasma prothrombin concentration and the degradation rate of serum "prothrombin-converting factor" during dicumarol therapy.

on fibrinogen and oxalated plasma revealed that serum obtained from recently coagulated whole blood contains a factor which causes conversion of prothrombin to thrombin.” 2 Since fibrinogen could not be converted to fibrin in any significant degree by addition of fresh serum, and since the rapidity of coagulation of oxalated plasma by the serum factor was proportional to the prothrombin concent...

The control of dicumarol therapy in myocardial infarction by a simple blood prothrombin test.

Effective anticoagulant therapy is dependent upon adequate and reliable blood prothrombin deter minations. The initiation of such therapy usually requires hospitalization. The currently available blood prothrombin tests require special laboratory facilities and trained personnel. The authors of this report present the results of Dicumarol in myocardial infarction and a simple blood prothrombin ...

The effect of dicoumarol on co-thromboplastin, a factor in blood concerned with the conversion of prothrombin to thrombin.