Recurrent thromboembolism after splenectomy in a patient with complex hemoglobin disease: a case report
نویسندگان
چکیده
Some hematological diseases can benefit from splenectomy for either diagnosis or treatment. When dealing with patients with thalassemia, splenectomy is a common therapeutic option, particularly indicated when the patient has increased transfusion demand, symptomatic splenomegaly or any signs of poor health, leucopenia, and thrombocytopenia.1 However, splenectomy can lead to thromboembolic events, particularly in splenectomized patients with thalassemia intermedia.1,2 Thromboembolic complications in splenectomized patients with complex hemoglobin diseases are seldom reported due to the rarity of these conditions. We therefore report a case of a woman with hemoglobin (Hb) C/ 0-thalassemia and recurrent venous thromboembolism after splenectomy. The patient and all family members signed a consent form.
منابع مشابه
Post Splenectomy Fatal Pulmonary Embolism in a Patient with Moderate Hemophilia A
Hemophilia A is a bleeding disorder caused by defective production of factor VIII. The main concern associated with the disease is bleeding, especially after trauma and surgeries. Factor VIII replacement therapy is associated with substantial decrease of bleeding events during surgery. However, there have been a number of reports of thromboemblic events in this situ-ation. The present report de...
متن کاملRecurrent Venous Thromboembolism as the Initial Clinical Presentation of Gastric Cancer: A Case Report
Pulmonary thromboembolism (PTE) is a clinically critical disease, misdiagnosis or delayed diagnosis of which can lead to increased rate of mortality. For prevention of recurrence of PTE, recognition of its risk factors or underlying diseases is of great importance. PTE is common in patients with cancer and has high morbidity and mortality rates. Although cancer is a lethal condition, PTE accele...
متن کاملAnalysis of the genetic variants associated with recurrent thromboembolism in a patient with hemoglobin H disease following splenectomy: A case report
Reports of recurrent thromboembolism in thalassemia, particularly in hemoglobin H (HbH) disease associated with congenital thrombophilic mutations, are scarce. However, several mutations were detected in a 22-year-old woman with HbH disease. The patient experienced the first thrombotic event at the age of 20 years and had four recurrent thromboses in a short time interval, despite receiving ant...
متن کاملPrimary Splenic Tuberculosis in a 43-Year-Old Female Patient in Fatemi Hospital of Ardebil: A Case Report
Background and Objectives: Tuberculosis (TB) is included within the top ten causes of death worldwide. This disease is associated with pulmonary and extrapulmonary involvement. The major extra pulmonary organs involved in the disease, are lymph nodes, pleura, genitourinary tract, bones, and meningeal tissue. Primary splenic infection is one of the rare complications of TB. Case Report: Patie...
متن کاملTreatment of recurrent genital Herpes with Imiquimod: A case report
In this report, a 32 year-old patient is reported who was suffering from recurrent genital herpes for 3 years and her disease could not be controlled with conventional treatment methods. But, application of Imiquimod 5% cream, 3 times a week for 3 months, proved very effective with no recurrence for up to 7 months. Since recurrent genital herpes is the result of some immunologic dysfunctions ca...
متن کامل