Management of acneiform rashes related to gefitinib therapy.
نویسنده
چکیده
JUNE 2004 • VOLUME 8, NUMBER 3 • CLINICAL JOURNAL OF ONCOLOGY NURSING Michelle Purdom, RN, BSN, is a research nurse supervisor in the Department of Cancer Medicine Phase 1 Unit at the University of Texas M.D. Anderson Cancer Center in Houston. (Mention of specific products and opinions related to those products do not indicate or imply endorsement by the Clinical Journal of Oncology Nursing or the Oncology Nursing Society.)
منابع مشابه
Management of EGFR-inhibitor associated rash: a retrospective study in 49 patients
BACKGROUND In recent years inhibitors directed against the epidermal growth factor receptor (EGFR) have evolved as effective targeting cancer drugs. Characteristic papulopustular exanthemas, often described as acneiform rashes, are the most frequent adverse effect associated with this class of novel cancer drugs and develop in > 90% of patients. Notably, the rash may significantly compromise th...
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متن کاملCutaneous Side Effects and Transepidermal Water Loss To Gefitinib: A Study of 11 Patients
INTRODUCTION Cutaneous side effects caused by epidermal growth factor receptor (EGFR) inhibitors occurred in 45-100% of patients which may lead to therapy modification or interruption. This study aimed to evaluate cutaneous side effects and transepidermal water loss (TEWL) values in non-small cell lung carcinoma (NSCLC) patients who received gefitinib EGFR inhibitor. METHODS A descriptive obs...
متن کاملChanges in sebum levels and the development of acneiform rash in patients with non–small cell lung cancer after treatment with EGFR inhibitors
BACKGROUND It has recently been shown that patients treated with epidermal growth factor receptor (EGFR) inhibitors often develop various cutaneous adverse events. While the pathogenesis underlying these events remains unclear, the relationship between skin toxicity induced by EGFR inhibitors and the sebaceous glands that express EGFR has been previously reported. OBJECTIVES The primary aim o...
متن کاملPressure sore-like ulcers on acneiform papules caused by EGFR inhibitors.
Dear Editors, Epidermal growth factor receptor (EGFR) inhibitors such as erlotinib and gefitinib have been established as effective therapies for non-small cell lung cancer, pancreatic cancer, colorectal cancer, and head and neck cancer (1). However, a number of skin manifestations, such as acneiform papules, xerosis, photosensitive dermatitis, pruritus, perionychia and vasculitis have been rep...
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ورودعنوان ژورنال:
- Clinical journal of oncology nursing
دوره 8 3 شماره
صفحات -
تاریخ انتشار 2004