bowenoid transformation in seborrheic keratosis: a retrospective analysis of 429 patients

نویسندگان

parvin rajabi professor, department of pathology, school of medicine, isfahan university of medical sciences, isfahan, iran

neda adibi assistant professor, psychosomatic research center, school of medicine, isfahan university of medical sciences, isfahan, iran

pardis nematolahi assistant professor, department of pathology, school of medicine, isfahan university of medical sciences, isfahan, iran

mitra heidarpour associated professor, department of pathology, school of medicine , isfahan university of medical sciences, isfahan, iran

چکیده

background : seborrheic keratosis is a common, benign skin tumor. numerous reports have shown its possibility of malignant transformation. this study was designed to demonstrate the occurrence of concomitant seborrheic keratosis and skin cancers. methods : data was retrospectively reviewed from all patients with a diagnosis of seborrheic keratosis in pathology department of alzahra hospital and a private pathology laboratory in isfahan, iran over a 4-year period. we classified all demographic data and associated dysplasia or bowen's disease and analyzed them by student-t or chi-square tests. results : from all 429 specimens, 5 (1.2%) were found to be associated with bowen's disease and one (0.2%) with mild dysplasia in squamous epithelium . all cases arose within the clinically, atypical seborrheic keratosis. more men were affected with lesions alone and with malignancy (230/423 (54.4%) and 5/6 (83.3%), respectively) compared to women. the average age of patients suffering from lesions with and without associated malignancy was 57 and 54 years, respectively. the common site of lesion alone was head and neck but lesions with malignancy involved lower extremities. the two lesions were significantly different in site of occurrence (p < 0.001). conclusions : generally, although the association between seborrheic keratosis and skin malignancy appears to be accidental, it must always be in mind. therefore, histopathologic examination of all seborrheic keratosis should be considered, especially when seborrheic keratosis has atypical clinical manifestations. keywords : keratosis seborrheic, bowen's disease, dysplasia

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Bowenoid transformation in seborrheic keratosis: A retrospective analysis of 429 patients

BACKGROUND Seborrheic keratosis is a common, benign skin tumor. Numerous reports have shown its possibility of malignant transformation. This study was designed to demonstrate the occurrence of concomitant seborrheic keratosis and skin cancers. MATERIALS AND METHODS Data was retrospectively reviewed from all patients with a diagnosis of seborrheic keratosis in pathology department of Alzahra ...

متن کامل

Association of pulmonary leiomyoma with seborrheic keratosis

A 58 year old man was referred to suegery clinic due to dyspnea and left sided chest wall pain for three months duration.during the last 18 months some monomorph disseminated hyperkeratotic skin lesions appeared on his face and trunk.after worlup and evaluation of the patient,he underwent thoracotomy with indication of presence of a mass in the left lung.the operative finding was a huge solid r...

متن کامل

Dermatofibroma simulating seborrheic keratosis dermoscopically*

Dermatofibroma is a frequent benign tumor of easy clinical diagnosis in most cases, but that can mimic other dermatoses. Dermoscopy may help to define the diagnosis and its classical pattern is a central white area, similar to a scar, surrounded by a discrete pigment network. However, dermoscopic findings are not always typical. We describe here a case of dermatofibroma exhibiting ridges, furro...

متن کامل

[Seborrheic keratosis of conjunctiva: a case report].

CASE REPORT Pigmented conjunctival lesions are a diagnostic challenge for the clinician. A 37-year-old man presented with a pigmented mass involving the conjunctiva of his right eye. Clinically, a diagnosis of malignant melanoma was made and a wide excision of the tumor was performed. The histopathologic diagnosis was seborrheic keratosis. DISCUSSION Seborrheic keratosis is a benign lesion wh...

متن کامل

Dermatoscopic Findings of Seborrheic Keratosis in Melanoma.

Cutaneous melanoma may in some instances be confused with seborrheic keratosis, which is a very common neoplasia, more often mistaken for actinic keratosis and verruca vulgaris. Melanoma may clinically resemble seborrheic keratosis and should be considered as its possible clinical simulator. We report a case of melanoma with dermatoscopic characteristics of seborrheic keratosis and emphasize th...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
journal of research in medical sciences

جلد ۱۷، شماره ۳، صفحات ۰-۰

کلمات کلیدی

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023