evaluating sex hormone levels in reproductive age women with multiple sclerosis and their relationship with disease severity

نویسندگان

azam foroughipour department of midwifery, islamic azad university, najaf abad branch, isfahan, iran

vajihe norbakhsh department of midwifery, islamic azad university, najaf abad branch, isfahan, iran

sara h najafabadi isfahan medical research center, isfahan university of medical sciences, isfahan, iran

rokhsareh meamar isfahan neurosciences research center, isfahan university of medical sciences and department of medical science, islamic azad university, najaf abad branch, isfahan, iran

چکیده

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: sex-related differences in the severity of multiple sclerosis (ms) could be influenced by the sex hormones. materials and methods: this cohort (historical) study evaluated the sex hormone levels during menstrual cycle and their correlation with disease severity in ms. result: patients with ms had significantly lower testosterone, dehydroepiandrosterone sulfate, and prolactin levels than controls in the follicular and luteal phase but lower estradiol levels only in the follicular phase. a positive correlation coefficient between follicle stimulating hormone and disease severity, and a reverse correlation with estradiol were found. conclusion: the hormone-related modulation of disease severity supports the suggestion that sex hormones play a role in ms disease .

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Evaluating sex hormone levels in reproductive age women with multiple sclerosis and their relationship with disease severity

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عنوان ژورنال:
journal of research in medical sciences

جلد ۱۷، شماره ۹، صفحات ۰-۰

کلمات کلیدی
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