n-acetylcysteine for treatment of autism, a case report

نویسندگان

ahmad ghanizadeh research center for psychiatry and behavioral sciences and department of psychiatry, shiraz university of medical sciences, school of medicine, shiraz, iran

nima derakhshan research center for psychiatry and behavioral sciences, shiraz university of medical sciences, school of medicine, shiraz, iran

چکیده

there are a limited number of food and drug administration ( fda)-approved medications for the treatment of autism. meanwhile, oxidative stress and neuroinflammation are supposed to play a causative role in autism. n-acetylcysteine may provide cystine, a precursor for glutathione (gsh), which is an important antioxidant factor in the brain. we here report a child with autism, whose symptoms were markedly decreased after taking oral n-acetylcysteine 800 mg / day, in three divided doses. his social interaction was significantly increased. the score of social impairment on a visual analog scale decreased from 10 to 6 in the two-month trial. the aggressive behaviors decreased from 10 to 3. this case suggests that n-acetylcysteine may decrease some symptoms of autism.

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عنوان ژورنال:

journal of research in medical sciences

جلد ۱۷، شماره ۱۰، صفحات ۰-۰

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