does omega‑3 supplement enhance the therapeutic results of methylphenidate in attention deficit hyperactivity disorder patients?

نویسندگان

fatemeh behdani associate professor of psychiatry, mashhad university of medical sciences, mashhad, iran

paria hebrani associate professor of child and adolescent psychiatry, mashhad university of medical sciences, mashhad, iran

afshin naseraee psychiatrist, mashhad university of medical sciences, mashhad, iran

mehri baghban haghighi medical practitioner, mashhad university of medical sciences, mashhad, iran

چکیده

normal 0 false false false en-us x-none ar-sa background: although most of the adhd (attention deficit hyperactivity disorder) patients respond to stimulant drugs very well,alternative drugs are required for non respondents. it has been revealed that subgroups of patients with adhd have omega-3 fatty acid deficiency. so, the present study was planned to illustrate the effect of omega‑3 supplementation, as an add‑on to methylphenidate,on adhd patients. materials and methods: in this double-blind rct, adhd children without any co morbidity, who had been diagnosed by a child and adolescent psychiatrist in child and adolescent university clinic, participated and were randomly divided into 2 groups. the experimental group methylphenidate plus omega‑3 capsule (2000mg/d), while control group took methylphenidate plus placebo. severity of adhd symptoms were assessed by adhd rating scale at the baseline and after 2, 4 and 8 weeks of treatment. results: 69 patients (experimental = 36, control = 33) aged 7 to 15 participated. a significant reduction of both parent’s and teacher’s adhd rating scale scores in both groups was observed. bu t it couldn’t show any difference between two groups. difference score of parent’s at baseline was 1.86 ± (5/40), pv 0.262, after 2 weeks -0.70 ± (4/30), pv 0.668,4 weeks. 19 ± (5/60), pv 0.902 and 8 weeks. 30 ± (4/42), pv 0.845. difference score of teacher’s at baseline was -1.56 ± (3/45), pv 0.541, after 2 weeks -0.46 ± (6/24),pv 0.888, 4 weeks. 45 ± (5/41), 0.868 and 8 weeks. 73+‑ (4/18), pv 0.748. conclusion: omega-3 did not enhance the therapeutic results of methylphenidate in adhd patients.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Methylphenidate for Attention-Deficit/Hyperactivity Disorder.

know about the risks of the procedure. Do the benefits outweigh the risks? Jurors in states with the reasonablepatient standard can ask themselves, “Would I have wanted to know about this risk?” “Would it have affected my decision making?” Drs Drolet and Brower also express concerns about operationalizing the reasonable-patient standard. They argue that each patient’s informational needs are un...

متن کامل

The effect of cognitive rehabilitation on the improvement of attention deficit disorder in patients with attention deficit hyperactivity disorder.

The purpose of the present study was to investigate the effect of cognitive rehabilitation on the improvement of attention deficit disorder in patients with hyperactivity disorder, based on quasi-experimental and pretest-posttest design with control group. The statistical population consisted of all patients with a diagnosis of attention deficit hyperactivity disorder (ADHD) in Roozbeh Psychiat...

متن کامل

Methylphenidate Transdermal System in Attention-Deficit Hyperactivity Disorder in Adolescentsy

Attention-deficit hyperactivity disorder (ADHD) is characterized by inattention, hyperactivity, and impulsivity. Globally, ADHD affects approximately 5–10% of children and persists into adolescence in up to 85% of affected individuals. Psychostimulants, such as methylphenidate and amfetamine, are the mainstay of treatment in ADHD. A patch that delivers methylphenidate transdermally (methylpheni...

متن کامل

Methylphenidate for Attention-Deficit/Hyperactivity Disorder in Children and Adolescents.

CLINICAL QUESTION Is treatment with methylphenidate associated with benefits or harms for children and adolescents with attention-deficit/hyperactivity disorder (ADHD)? BOTTOM LINE Methylphenidate is associated with improvement in ADHD symptoms, general behavior, and quality of life; however, due to the very low quality of the evidence, the magnitude of the associated improvement is uncertain...

متن کامل

Combined methylphenidate and atomoxetine pharmacotherapy in attention deficit hyperactivity disorder.

OBJECTIVES Pharmacological treatment of attention deficit hyperactivity disorder (ADHD) includes stimulant and non-stimulant medications. Our purpose in this study is to investigate efficacy, safety and tolerability of combined methylphenidate and atomoxetine pharmacotherapy. METHODS We included 12 patients of the 824 patients with ADHD using methylphenidate and atomoxetine combined therapy b...

متن کامل

Methylphenidate use in children with attention deficit hyperactivity disorder

A Brazilian Health Technology Assessment Bulletin (BRATS) article regarding scientific evidence of the efficacy and safety of methylphenidate for treating attention deficit hyperactivity disorder (ADHD) has caused much controversy about its methods. Considering the relevance of BRATS for public health in Brazil, we critically reviewed this article by remaking the BRATS search and discussing its...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
journal of research in medical sciences

جلد ۱۸، شماره ۸، صفحات ۶۵۳-۰

کلمات کلیدی
[ ' a t t e n t i o n d e f i c i t h y p e r a c t i v i t y d i s o r d e r ' , ' m e t h y l p h e n i d a t e ' , ' o m e g a ' , ' 3 r n / * s t y l e d e f i n i t i o n s * / r n t a b l e . m s o n o r m a l t a b l e r n t { m s o ' , ' s t y l e ' , ' n a m e ' , ' & ' , ' q u o t ' , ' t a b l e n o r m a l & ' , ' q u o t ' , ' m s o ' , ' t s t y l e ' , ' r o w b a n d ' , ' s i z e ' , 0 , ' m s o ' , ' t s t y l e ' , ' c o l b a n d ' , ' s i z e ' , 0 , ' m s o ' , ' s t y l e ' , ' n o s h o w ' , ' y e s ' , ' m s o ' , ' s t y l e ' , ' p r i o r i t y ' , 9 9 , ' m s o ' , ' s t y l e ' , ' q f o r m a t ' , ' y e s ' , ' m s o ' , ' s t y l e ' , ' p a r e n t ' , ' & ' , ' q u o t ' , ' & ' , ' q u o t ' , ' m s o ' , ' p a d d i n g ' , ' a l t ' , ' 0 i n 5 . 4 p t 0 i n 5 . 4 p t ' , ' m s o ' , ' p a r a ' , ' m a r g i n ' , ' t o p ' , ' 0 i n ' , ' m s o ' , ' p a r a ' , ' m a r g i n ' , ' r i g h t ' , ' 0 i n ' , ' m s o ' , ' p a r a ' , ' m a r g i n ' , ' b o t t o m ' , ' 1 0 . 0 p t ' , ' m s o ' , ' p a r a ' , ' m a r g i n ' , ' l e f t ' , ' 0 i n ' , ' l i n e ' , ' h e i g h t ' , ' 1 1 5 % ' , ' m s o ' , ' p a g i n a t i o n ' , ' w i d o w ' , ' o r p h a n ' , ' f o n t ' , ' s i z e ' , ' 1 1 . 0 p t ' , ' f o n t ' , ' f a m i l y ' , ' & ' , ' q u o t ' , ' c a l i b r i & ' , ' q u o t ' , ' & ' , ' q u o t ' , ' s a n s ' , ' s e r i f & ' , ' q u o t ' , ' m s o ' , ' a s c i i ' , ' f o n t ' , ' f a m i l y ' , ' c a l i b r i ' , ' m s o ' , ' a s c i i ' , ' t h e m e ' , ' f o n t ' , ' m i n o r ' , ' l a t i n ' , ' m s o ' , ' f a r e a s t ' , ' f o n t ' , ' f a m i l y ' , ' & ' , ' q u o t ' , ' t i m e s n e w r o m a n & ' , ' q u o t ' , ' m s o ' , ' f a r e a s t ' , ' t h e m e ' , ' f o n t ' , ' m i n o r ' , ' f a r e a s t ' , ' m s o ' , ' h a n s i ' , ' f o n t ' , ' f a m i l y ' , ' c a l i b r i ' , ' m s o ' , ' h a n s i ' , ' t h e m e ' , ' f o n t ' , ' m i n o r ' , ' l a t i n ' , ' m s o ' , ' b i d i ' , ' f o n t ' , ' f a m i l y ' , ' a r i a l ' , ' m s o ' , ' b i d i ' , ' t h e m e ' , ' f o n t ' , ' m i n o r ' , ' b i d i ' , ' } ' ]

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023