evaluation of antifungal activity of essential oils of thymus vulgaris, petroselinum crispum, cuminum cyminum and bunium persicum on candida albicans in comparison with fluconazole

نویسندگان

farnoosh haghighi

shahla roudbar mohammadi

neda soleimani

morteza sattari

چکیده

objective: nowadays notable increase in acquired resistance of candida species to antifungal drugs and necessity of using agents with antifungal properties is unavoidable. in some plants due to presence of components such as polyphenols have antimicrobial properties. in this study antifungal effects of essential oils of thymus vulgaris, petroselinum crispum, cuminum cyminum and bunium persicum on standard strain of candida albicans were evaluated. materials and methods: 25 grams leafs of the thymus vulgaris and petroselinum crispum and seeds of the cuminum cyminum and bunium persicum were dried and grinded after that the essential oils of each mentioned plant were prepared by clevenger system. serial dilutions of essential oils were made in 96 well microtiter plates. minimum inhibitory concentration (mic) and inhibitory zone diameter were assessed by microdilution broth and disc diffusion agar techniques, mic50, mic90 and mfc were also determined. results: minimum inhibitory concentration 90(mic90) essential oils of thymus vulgaris, petroselinum crispum, cuminum cyminum and bunium persicum were respectively 25, 72, 412, 130 µg/ml and minimal fungicide concentration (mfc) were 48, 146, 62, 280. inhibitory zone diameters were 28, 20, 12, 15 millimetres. conclusion: in this evaluation essential oils of thymus vulgaris, petroselinum crispum, cuminum cyminum and bunium persicum showed suitable antifungal effects against growth of standard strain of candida albicans. thus these herbal essences after supplementary studies possibly can be suitable substitute for chemical medicine on candida infections especially on mucocutaneous candidiasis.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Antifungal activity of essential oils from Iranian plants against fluconazole-resistant and fluconazole-susceptible Candida albicans

Objectives: The purpose of this study was to assay the antifungal activity of selected essential oils obtained from plants against both fluconazole (FLU)-resistant and FLU-susceptible C. albicans strains isolated from HIV positive patients with oropharyngeal candidiasis (OPC). Materials and Methods: The essential oils were obtained by hydrodistillation method from Myrtus communis (My. communis)...

متن کامل

Investigating the Phytochemical, Antibacterial and Antifungal Effects of Thymus Vulgaris and Cuminum Cyminum Essential Oils

Abstract       Background and Objective: The aim of this study was to determine the chemical composition, antibacterial and antifungal effects of Thymus vulgaris and Cuminum Cyminum essential oils against foodborne pathogens and Candida species in vitro.       Methods: The essential oils were extracted from the aerial parts of Thymus vul...

متن کامل

Antifungal effect of essential oil of Bunium persicum on Candida albicans, In vitro study

Introduction: Bunium persicum is a gramine plant from Umbelliferae family. Candida albicans is a kind of yeast known as normal flora of skin and gastrointestinal tract (GIT), respiratory and genitourinary (GU) mucosa. This fungi makes disease in immunodeficient individuals. The aim of this study was to assess the antifungal effect of essential oil of Bunium persicum on Candida albicans. Methods...

متن کامل

Antifungal activity of essential oils from Iranian plants against fluconazole-resistant and fluconazole-susceptible Candida albicans

OBJECTIVE The purpose of this study was to assay the antifungal activity of selected essential oils obtained from plants against both fluconazole (FLU)-resistant and FLU-susceptible C. albicans strains isolated from HIV positive patients with oropharyngeal candidiasis (OPC). MATERIALS AND METHODS The essential oils were obtained by hydrodistillation method from Myrtus communis (My. communis),...

متن کامل

In vitro antifungal activity of essential oils extracted from plants against fluconazole-susceptible and -resistant Candida albicans

Backgrounds and aims: Candida albicans is more prevalent between Candida species which can cause candidal infection. Various studies have shown drug resistance among the C. albicans isolates, so it is now necessary to discover replacement treatments for the Candida infection. The aim of this study is comparison the effects of different Essential oils (EOs) against azoles-resistant and azoles-su...

متن کامل

antifungal activity of essential oils from iranian plants against fluconazole-resistant and fluconazole-susceptible candida albicans

objectives: the purpose of this study was to assay the antifungal activity of selected essential oils obtained from plants against both fluconazole (flu)-resistant and flu-susceptible c. albicans strains isolated from hiv positive patients with oropharyngeal candidiasis (opc). materials and methods: the essential oils were obtained by hydrodistillation method from myrtus communis (my. communis)...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
modares journal of medical sciences: pathobiology

ناشر: tarbiat modares university

ISSN 1562-9554

دوره 14

شماره 1 2011

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023