the kinetic parameters of drug compounds adsorption onto mesoporous materials

نویسندگان

masoud. giahi

abdollah. falah shojaie

farkhondeh. mirsfa moqadam

چکیده

the discovery of mesoporous molecular sieves, mcm-41, which possesses a regular hexagonalarray of uniform pore openings, aroused a worldwide resurgence in this field. this is not onlybecause it has brought about a series of novel mesoporous materials with various compositionswhich may find applications in catalysis, adsorption, and guest-host chemistry, but also it hasopened a new avenue for creating of the zeotype materials. this paper presents a comprehensiveoverview of recent advances in the field of mcm-41. adsorption of drug molecules such aspseudeoephedrine hydrochloride onto mesoporous molecular sieves (mcm-41) from aqueoussolution has been investigated systematically using batch experiments in this study. resultsindicate that pseudeoephedrine hydrochloride adsorption is initially rapid and the adsorptionprocess reaches a steady state after 2 min. the adsorption isotherms are well described by thelangmuir model. based on the results, it suggests that the adsorption is primarily brought about byhydrophobic interaction between drug molecules and mcm-41 surface.

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عنوان ژورنال:
journal of physical & theoretical chemistry

ISSN

دوره 5

شماره 1 2008

کلمات کلیدی
[ ' m c m ' , 4 1 , ' p s u d e o e p h e d r i n e h y d r o c h l o r i d e ' , ' d e s o r p t i o n ' , ' a d s o r p t i o n ' ]

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