lipid concentration at 13-23 weeks of pregnancy and the risk of abnormal glucose challenge test (gct)
نویسندگان
چکیده
abstract objective: the aim of this study was evaluating the relationship between maternal serum lipid measured at 13-23 weeks of pregnancy and subsequent glucose intolerance. materials and methods: in a prospective study, 624 pregnant women prior to 23 weeks were eligible for the study. primarily, serum levels of total cholesterol, ldl cholesterol, hdl cholesterol, and triglyceride were measured. women were grouped according to tertiles determined by the distribution of maternal serum lipid concentration among the entire cohort. then, all patients at 24-28 gestation weeks were screened with a 50gr oral glucose test. the prevalence of abnormal gct was compared among the lipid profile tertiles. results: the number of women with abnormal gct was less in the group with tg concentration in lower tertile in comparison with the groups with tg concentrations in the higher and middle tertile (p<0.001, p=0.004 respectively) . conclusion: triglyceride levels early in pregnancy are associated with abnormal gct.
منابع مشابه
Lipid Concentration at 13-23 Weeks of Pregnancy and the Risk of Abnormal Glucose Challenge Test (GCT)
Abstract Objective: The aim of this study was evaluating the relationship between maternal serum lipid measured at 13-23 weeks of pregnancy and subsequent glucose intolerance. Materials and Methods: In a prospective study, 624 pregnant women prior to 23 weeks were eligible for the study. Primarily, serum levels of total cholesterol, LDL cholesterol, HDL cholesterol, and triglyceride were ...
متن کاملLipid Concentration at 13-23 Weeks of Pregnancy and the Risk of Abnormal Glucose Challenge Test (GCT)
n normal pregnancy, there is a major alteration in maternal lipid profile. Pregnancy may increase 300% triglyceride (TG) level, 25-50% increase in total cholesterol (TC), high density cholesterol (HDL) and low density lipoprotein (LDL) (1,2). In gestational diabetes, exaggerated hypertriglyceridemia has been found in the first, second and third trimesters of pregnancy compared to normal pregnan...
متن کاملبررسی ارتباط لیپدهای خون زنان باردار در هفتههای 13 تا 23 بر مختل شدن تست رقابت گلوکز
Background and Objective: Gestational diabetes mellitus (GDM) complicates 3-5% of all pregnancies. Glucose Challenge Test (GCT) is a universal screening test for GDM between 24-28 of gestation. Plasma glucose is measured 1 hr after ingestion of 50g glucose load. The aim of this study was to determine the relationship of plasma lipids in 13-23 weeks of pregnancy with abnormal GCT (Glucose Challe...
متن کاملThe Impact of Maternal Age, Pre-Pregnancy Body Mass Index,Weight Gain and Parity on Glucose Challenge Test (GCT)
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عنوان ژورنال:
iranian journal of diabetes and obesityجلد ۷، شماره ۱، صفحات ۷-۱۱
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