unexplained infertility as primary presentation of celiac disease, a case report and literature review

background: celiac sprue (gluten sensitive enteropathy) is an autoimmune disease which is hereditary and its pathology mainly bases on immunologic intolerance to gluten. it has a vast variety of signs and symptoms and its clinical features range from a silent disease to a typical gastrointestinal disorder. in this study we reviewed and summarized some other related issues about this disease and its relation with infertility. case: the case is a 26 years old lady who had referred to a gynecologist because of infertility for 2 years and later it revealed that she has celiac sprue. conclusion: screening for its silent or subtle types especially among suspicious cases such as unexplained infertility seems to be a cost effective action. meanwhile, in time administration of a gluten-free diet can lead to an almost complete cure