transvaginal sonographic assessment of the follicular development and endometrial thickness in spontaneous and clomiphene citrate-induced cycles
نویسندگان
چکیده
objective: to assess follicular development and endometrial growth using transvaginal sonography in spontaneous and clomiphene citrate induced (cc) cycles. materials and methods: one hundred consecutive couples with unexplained infertility were recruited for this cross sectional study from 2003 to 2005. patients were monitored for the first cycle with no medication while the laboratory routine test results were being prepared. clomiphene citrate (150 mg) was administered on days 5 to 9 of cycle in 60 women. the pattern of the follicular development and endometrial growth was evaluated between clomiphene citrate-induced cycles and spontaneous cycles. spss software and student t test were used for analyzing the results. p value less than 0.05 was considered for statistical significance. results: the patterns of follicular development and endometrial growth were similar in both study cycles. conclusion: clomiphene citrate-induced cycles did not show different follicular and endometrial growth patterns compared with spontaneous cycles, so this must be regarded in treatment decision making.
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P-227: The Survey on Endometrial Thickness and Echo Pattern Changes in Consecutive Cycles of Clomiphene Citrate Therapy in Infertile Women
Background: One of the most common causes of infertility in women is ovulatory dysfunction (PCOS) and the choice of treatment is clomiphene citrate. One of the mechanism of dichotomy between the rate of ovulation and pregnancy is anti estrogenic effects of clomiphene citrate on endometrium. According to its long half life, the anti estrogenic effects probably exacerbate in consecutive cycles. W...
متن کاملA prospective study for the assement of follicular growth, endometrial thichness and serum estradioal levels in spontaneous and clomiphene citrate induced cycles in unexplained infertility patients
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The effect of administering vaginal estrogen to clomiphene citrate stimulated cycles on endometrial thickness and pregnancy rates in unexplained infertility.
OBJECTIVE Clomiphene citrate (CC) has some negative effects on the endometrium. We aimed to determine the effect of vaginally administered local estrogen (LE) on endometrial thickness (ET) and pregnancy rates in CC stimulated cycles. MATERIAL AND METHODS This was a prospective randomized crossover study that took place in a university hospital. The patients had received CC due to unexplained ...
متن کاملAssessment of endometrial perfusion with Doppler ultrasound in spontaneous and stimulated menstrual cycles.
OBJECTIVE Endometrial perfusions were measured by Doppler ultrasound to evaluate the influence of spontaneous menstrual cycles and to study the effect of clomiphene citrate. METHODS Flow waveforms in right and left uterine arteries were obtained by using transvaginal color Doppler ultrasonography in infertile women with 60 spontaneous menstrual cycles and 37 clomiphene citrate stimulated cycl...
متن کاملClomiphene citrate-induced follicular development in the presence of an ovarian ectopic pregnancy.
OBJECTIVE To describe a case of a patient who had multiple follicular growth in the presence of an undiagnosed ectopic pregnancy (EP). DESIGN Case report. SETTING In vitro fertilization unit at a university hospital. PATIENT(S) A 34-year-old patient with secondary infertility. INTERVENTION(S) Superovulation with clomiphene citrate (CC) and IUI. MAIN OUTCOME MEASURE(S) Follicular devel...
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عنوان ژورنال:
journal of family and reproductive healthجلد ۲، شماره ۱، صفحات ۴۹-۵۱
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