genetic mutations that prevent pain in children

نویسندگان

زهره منتصری

zohreh montaseri holly fatemeh school of nursing & midwiferi, shiraz, iranدانشکده پرستاری و مامایی حضرت فاطمه (ع)، شیراز، ایران آذر نعمت اللهی

azar nematollahi رکسانا جان قربان

roxana jan ghorban

چکیده

the primary function of pain is to warn the organism against dangers threatening its integrity. pain does serve as a warning signal for impending injuries. in some people, particularly young children. pain perception has been absent. congenital intesitivity to pain with anhidrosis (cipa) is rare genetic disease characterized by absence of reaction to noxious stimuli and anhidrosis. in this review article we evaluated since 2002. gipa is an autosomal recessive disease related to a mutation in the trk gene, characterized by inability to sweat, insensitivity to pain, recurrent episodes of hyperpyrexia, normal intelligence and development. when infant is diagnosed with congenital indifference to pain, he/she could neither feel nor percep the meaning of pain educating and maintaining an open consistent relationship with the family and caregivers are essential to reduce the morbidity of this condition .

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عنوان ژورنال:
genetics in the 3rd millennium

جلد ۶، شماره ۳، صفحات ۱۴۳۳-۱۴۳۳

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