approach to leukodystrophies in infancy and childhood

نویسندگان

بیتا بزرگمهر

bita bozorgmehr 1143 med bldg, sanat sq, shahrak ghods (gharbtehran, iran, p.o. box 14665/154)

چکیده

leukodystrophies are familial disorders with onset usually in infancy or childhood. the name comes from the greek leuko meaning white and dystrophy meaning imperfect growth or development. leukodystrophy is a progressive, genetic disorder with an autosomal recessive or x-linked mode of inheritance. the clinical features consist of motor dysfunction with varying degrees of cognitive decline. magnetic resonance imaging and biochemical enzymatic and genetic tests have a great role in identification of leukodytrophies. important advances in our understanding of genetic disorders of the white matter help families who have affected children.

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عنوان ژورنال:
genetics in the 3rd millennium

جلد ۷، شماره ۳، صفحات ۱۷۷۰-۱۷۷۰

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