ulcerative colitis associated with chronic granulomatous disease: case report
نویسندگان
چکیده
chronic granulomatous disease (cgd) is an inherited primary immunodeficiency disease which increases the body’ssusceptibility to infections caused by certain bacteria and fungi. cgd is a rare disease, caused by four genes, one type is 1xlinked and the other three are “autosomal recessive”. although clinical presentation is variable, but characteristic featuresare recurrent pneumonia, lymphadenitis, hepatic or other abscesses. gastrointestinal tract symptoms are common in xlinkedrecessive form of cgd. these include gastric and esophageal obstruction and inflammatory bowel disease. giinvolvement including small and large intestines, the findings of luminal narrowing and the presence of granuloma canmake it difficult to distinguish from crohn’s disease. on the other hands according to the literature ulcerative colitis israrely reported in patients with cgd. our case presented with ulcerative colitis with cgd.
منابع مشابه
Ulcerative colitis associated with chronic granulomatous disease: case report
Chronic Granulomatous Disease (CGD) is an inherited primary immunodeficiency disease which increases the body's susceptibility to infections caused by certain bacteria and fungi. CGD is a rare disease, caused by four genes, one type is 1X linked and the other three are "autosomal recessive". Although clinical presentation is variable, but characteristic features are recurrent pneumonia, lymphad...
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BACKGROUND Involvement of the gut in chronic granulomatous disease (CGD) has been previously described and colitis highlighted. However, the nature and histopathology of the colitis are unclear and have been thought to be non-specific or similar to Crohn's disease. METHODS Seven patients with CGD, suffering from gastrointestinal symptoms were prospectively studied. RESULTS All patients had ...
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عنوان ژورنال:
gastroenterology and hepatology from bed to benchجلد ۸، شماره ۳، صفحات ۲۰۱۵-۸
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