β-d-glucan assay in diagnosis and monitoring the systemic candidiasis in a rat model

β-D-Glucan Assay in Diagnosis and Monitoring the Systemic Candidiasis in a Rat Model

BACKGROUND Determination of β-D-Glucan (BDG) in the serum aids to diagnose the invasive fungal infections. The current study evaluated the diagnostic potential value of BDG assay in monitoring the disease in experimental systemic candidiasis in a rat model. The results can provide a useful preliminary data to improve this approach in developing countries. OBJECTIVES The present study aimed to...

Experience with β-d-Glucan Assay for Diagnosis of Invasive Candidiasis in ICU Patients: Pilot Study from India

Serum (1->3)-Β-D-Glucan Assay for Diagnosis of Pneumocystis Pneumonia in Immunocompromised Patients

Copyright: © 2012 Fan LC. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Pneumocystis Pneumonia (PCP) is one of the most prevalent infections in Human Immunodeficiency Virus (HIV)-Infected Patients [1]. PCP a...

Performance of Candida real-time polymerase chain reaction, β-D-glucan assay, and blood cultures in the diagnosis of invasive candidiasis.

BACKGROUND The sensitivity of blood cultures for diagnosing invasive candidiasis (IC) is poor. METHODS We performed a validated Candida real-time polymerase chain reaction (PCR) and the Fungitell 1,3-β-D-glucan (BDG) assay on blood samples collected from prospectively identified patients with IC (n = 55) and hospitalized controls (n = 73). Patients with IC had candidemia (n = 17), deep-seated...

A real time PCR assay on blood for diagnosis of invasive candidiasis in immunocompromised patient

Background and Purpose: Invasive candidiasis (IC) is a significant cause of morbidity and mortality in patients with hematologic disorders and bone marrow transplant recipients. Rapid, specific and sensitive test for the timely accuracy in immunocompromised patients to reduce mortality rates and prevent IC progress is necessary. We established a real-time PCR assay on blood for the diagnosis an...

Assessment of Β-d-(1→3)-glucan Assay for Diagnosis of Invasive Fungal Infec- Tions

Aim: Invasive fungal infections (IFIs) are associated with high mortality and morbidity. However, the diagnosis of IFIs in an immunocompromised host is difficult and often missed or delayed. Our aim was to investigate the feasibility of the (1→3)-β-DGlucan assay as a diagnostic complement for IFIs. Methods: We reviewed the records of all inpatients in various units at Erciyes University’s Medic...