prevalence of virulence-related determinants in clinical isolates of staphylococcus epidermidis

conclusions prevalence of fbe and aap was significantly different from similar studies, yet frequency of bhp was in accordance with other studies. prevalence of icaa and is256 was not significantly different from some studies while a significant difference was observed when results were compared with some other studies. results of the 59 s. epidermidis, fbe was found in 89.8%, while aap and bhp were observed in 64.4% and 15.3% of the samples, respectively. coexistence of aap and fbe was found in 32 isolates, while coexistence of bhp and fbe was observed in five isolates. two isolates were negative for the investigated genes. materials and methods fifty-nine s. epidermidis isolates were collected from blood (50), wound (1), urine (4) and tracheal (4) samples (tehran, iran). staphylococcus epidermidis isolates were identified with conventional bacteriological tests. virulence-associated genes were detected by specific polymerase chain reactions (pcrs). background staphylococcus epidermidis, a member of the human flora, is recognized as an opportunistic pathogen and cause of nosocomial infections. staphylococcus epidermidis surface components are able to establish bacteria on the host surface, and cause infection. objectives the frequency of icaa, is256, aap, fbe and bhp in clinical isolates of s. epidermidis were investigated in this study.