efficacy of autologous fibrin glue for primary pterygium surgery with conjunctival autograft
نویسندگان
چکیده
purpose : to evaluate the efficiency and safety of using autologous fibrin glue for attachment of a conjunctival autograft in primary pterygium surgery methods : in this prospective interventional case series, 15 eyes from 13 patients with primary nasal pterygium were included for conjunctival autograft surgery. on the operation day, thrombin and fibrinogen were prepared from the patient’s own blood in two separate sealed tubes in the blood transfusion center. autologous fibrin glue was applied over the bare sclera for attachment of the free conjunctival autograft to the surrounding conjunctiva and sclera. the anatomic outcomes of flap, surgical time, recurrence rate, and other complications were evaluated on days 1, 3, and 7 and at months 1, 6, and 9 and 3 year after operation. a patient’s pain was evaluated using a 5-point scale from lim-bon-siong et al grading at all visits. results : of the 13 patients, 76.9% were male. the mean age of the patients was 37.26±12.61 (sd) years (range 23-60). the mean follow-up period was 34.67±2.96 months (range 25-36). three eyes (20%) developed autograft retraction that resolved completely with continued eye patching. two eyes (13.33%) developed total graft dehiscence, and sutures were used for reattachment of the graft in its correct position. two eyes (13.33%) developed recurrence of pterygium, one of them had already a total graft dehiscence. in 13 eyes (86.66%), the conjunctival grafts were appropriately adhered to the bed and surrounding conjunctiva without suturing in the final visit. in the first postoperative day, ocular pain was recorded as grade 1 in 11 eyes (73.3%), grade 2 in 3 eyes (20%), and grade 3 in 1 eye (6.6%). in all patients, ocular pain disappeared during the 5 days after operation, except for two patients who needed suturing for graft reattachment, in whom ocular pain continued for 2 weeks. no other complications were found during follow-up. conclusion : this case series suggests that autologous fibrin glue is a safe and useful alternative method for graft fixation in pterygium surgery. iranian journal of ophthalmology 201123(1):39-47 © 2011 by the iranian society of ophthalmology
منابع مشابه
[Conjunctival autologous transplantation using fibrin glue in primary pterygium].
PURPOSE To assess the rate of recurrence and complications after primary pterygium removal with conjunctival autograft using fibrin tissue adhesive. Secondarily, to compare these results with a retrospective series that underwent the same surgery using sutures. METHODS A hundred and six eyes of 100 patients who underwent surgery with fibrin glue were prospectively studied, while 58 eyes of 51...
متن کاملEfficacy of sutureless and glue free limbal conjunctival autograft for primary pterygium surgery.
INTRODUCTION There are numerous adjunctive measures described to reduce the recurrence rates after pterygium excision. OBJECTIVE To study the efficacy and complications of sutureless and glue free limbal conjunctival autograft for the management of primary pterygium over a period of one year. MATERIALS AND METHODS A prospective interventional case series was carried out in 40 consecutive ey...
متن کاملPterygium surgery with conjunctival limbal autograft with fibrin glue under topical anaesthesia with lignocaine 2% jelly.
OBJECTIVE To evaluate the efficacy of lignocaine 2 % jelly as topical anesthesia in pterygium surgery with conjunctival limbal autograft using fibrin glue. MATERIALS AND METHODS A non-randomized interventional study was carried out including twenty-one patients who presented with primary pterygium. Under 2% lignocaine jelly, surgical dissection of the pterygium, scraping of corneal bed with c...
متن کاملUse of fibrin glue in the management of recurrent pterygium by conjunctival autograft.
OBJECTIVE To evaluate whether use of fibrin glue instead of sutures for the treatment of recurrent pterygium with conjunctival auto-graft (CAG) further decreases its recurrence. METHODS A prospective, clinical open trial of 50 eyes of 50 patients with recurrent pterygium, who were randomly assigned to either, pterygium excision and CAG with fibrin glue (Group 1) or with 6 interrupted sutures ...
متن کاملFibrin glue versus sutures for attaching the conjunctival autograft in pterygium surgery: a prospective observer masked clinical trial.
AIMS To compare the degree of conjunctival autograft inflammation, subconjunctival haemorrhage (SCH) and graft stability following the use of sutures or fibrin glue (FG) during pterygium surgery. METHODS Prospective, observer masked, clinical trial. 40 eyes of 40 patients undergoing primary pterygium surgery with conjunctival autograft were allocated into two groups. Group 1 (n = 20) had FG (...
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عنوان ژورنال:
journal of current ophthalmologyجلد ۲۳، شماره ۱، صفحات ۳۹-۴۷
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