waldenstromâ´smacroglobulinemia in cryptogenic cirrhosis

نویسندگان

maryam rohban

arezou estakhri

seyedasadollah moosavi

ghodratollah montazeri

چکیده

the coexistence of waldenstromâ´s macrglobulinemia and cryptogenic cirrhosis has been rarely reported.we describe a 72-year-old man with compensated cryptogenic cirrhosis whose major clinical presentation was hyperviscosity syndrome. serum protein electrophoresis revealed the presence of an igm-kappa spike. lambda light chain was found in urine. bone marrow biopsy was performed, which showed at least 22%infiltration with atypical plasma cells. no bone lesion was found. bywaldenstromâ´smacroglobulinemia diagnosis, patient treated with melphalan, thalidomide and dexamethasone. after three weeks of treatment, his symptoms disappeared and serum immunoglobuline m decreased below 1000 mg/dl.

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