liver fibrosis in patients with chronic liver diseases: are laboratory tests useful to diagnosis?

Liver fibrosis in patients with chronic liver diseases: are laboratory tests useful to diagnosis?

The article published in Hepatitis Monthy on noninvasive assessment of liver fibrosis with the aspartate transaminasis to platelet ratio index (APRI) in patients with chronic liver disease by Yilmaz et al. (1), is interesting and very useful to permit a diagnosis and staging of fibrosis, although this index does not seem to have a high sensitivity and specificity. In recent years, efforts have ...

Can patients with chronic liver diseases withstand Ramadan fasting?

Ramadan is a sacred month for Muslims all around the world. During this lunar-based month, healthy adult Muslims are obligated to abstain from eating, drinking, smoking, or using oral medications from predawn to sunset. Followers will typically eat just after sunset and again before dawn (1). The Islamic lunar Hijri calendar is 11 days shorter than the Gregorian solar calendar, and therefore, t...

Determining the progression stages of liver fibrosis in patients with chronic hepatitis B

Introduction: Chronic hepatitis B (CHB) leads to liver fibrosis, its failure, and death in the long term. The stage of fibrosis in CHB patients can also be detected based on the biochemical markers. The aim of this study was to predict the state of liver fibrosis in CHB patients and determine the possibility of patients shifting from a given state to another one. Materials and Methods: This stu...

Prediction of Liver Fibrosis in Chronic Hepatitis B Patients by Using Score of Routine Laboratory Tests

Background: The prognosis and management of patients with chronic hepatitis B depend on the amount and progression of the liver fibrosis. Liver biopsy is currently the gold standard for staging of fibrosis and histological activity, but it is poor tolerated. Noninvasive methods are now used increasingly to reduce the need for liver biopsy. Our aim is to validate simpler model, consisting of rou...

Serum γ-glutamyl Transferase Levels, Insulin Resistance and Liver Fibrosis in Patients with Chronic Liver Diseases

BACKGROUND AND AIMS Serum levels of γ-glutamyl-transpeptidase(γ-GT) were associated with liver disease severity and metabolic alterations, which in turn are able to affect hepatic damage. In patients with nonalcoholic fatty liver disease (NAFLD), genotype 1 chronic hepatitis C (G1CHC) and chronic hepatitis B (CHB), we assessed the link between liver fibrosis and γ-GT serum levels, and we evalua...

aspartate transaminase to platelet ratio index (apri) to assess liver fibrosis in patients with chronic liver disease