surveillance system for hepatitis c infection: a practical approach

Surveillance system for hepatitis C infection: A practical approach

Hepatitis C virus (HCV) infection is a serious public health concern throughout the world. Despite its public health prominence, however, how surveillance systems for hepatitis C should be designed is still a challenging issue especially in developing countries such as Iran. Establishing a surveillance system needs an ongoing process of case investigation, data collection, analysis of data and ...

hepatitis c virus as a multifaceted disease: a simple and updated approach for extrahepatic manifestations of hepatitis c virus infection

A Novel Multi-Epitope Vaccine For Cross Protection Against Hepatitis C Virus (HCV): An Immunoinformatics Approach

Background: Hepatitis C virus (HCV) causes acute and chronic human hepatitis infections. Due to the high genetic diversity and high rates of mutations in the genetic material so far there is no approved vaccine against HCV. Materials and Methods: The aim of this study was to determination B and T cell conserved epitopes of E1 and E2 proteins from HCV and construction of a chimeric pepti...

Improving surveillance for acute hepatitis C.

Understanding patterns of newly acquired hepatitis C virus (HCV) infection is fundamental to assessing the impact of prevention and treatment interventions. However, identifying newly acquired cases is difficult, usually requiring documented testing before and after exposure. As the proportion of cases identified as newly acquired by current New South Wales surveillance methodologies is signifi...

Nosocomial Infection Surveillance System in Iran: Structures, Processes and Achievements

Background and Objectives: This article provides an overview of the national nosocomial infection surveillance system in Iran and its current status, achievements, and challenges.   Methods: All relevant reports, documents, and program guidelines, as well as published literature and surveillance data related to the nosocomial infection surveillance system in Iran were critically reviewed. Opi...

Molecular surveillance of hepatitis C.

With public health focusing on reduction of morbidity and mortality in the human population, transmission and virulence are major targets of molecular disease surveillance. Current molecular approaches to the detection of HCV transmission are based on phylogenetic analysis of intra-host HCV variants. Next-generation sequencing and mass spectrometry offer significant improvements in accuracy, th...