anticonvulsant effect of berberis integerrima l. root extracts in mice

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Anticonvulsant effect of Berberis integerrima L. root extracts in mice.

Berberis integerrima is a member of Berberidaceae family. Berberine is one of the main constituents of this plant, having neuroprotective effect on central nervous system diseases. In this study, the anticonvulsant activity of methanolic extract, and hydromethanolic fraction, and chloroform fraction of B integerrima was assessed. The anticonvulsant effect of B integerrima was investigated using...

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Antinociceptive effect of methanolic extract and alkaloid fractions of Berberis integerrima root in animal models

Objective: Berberis vulgaris has antioxidant, hepato--renal protective, antibacterial, lipid lowering, anti-inflammatory and antinociceptive activities. The genus Berberis, has another member called Berberisintegerrima which has not been studied for antinociceptive activity and therefore, this study was aimed to examine the antinociceptive effect oftotal extract and alkaloid fractions of Berber...

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Anticonvulsant effect of Satureja hortensis L. aerial parts extracts in mice

Objective: Regarding the anticonvulsant effects of Satureja hortensis (S. hortensis) in Avicenna’s book: canon of medicine; the present study was undertaken to evaluate the anti- eplileptic effects of S. hortensis aqueous and ethanolic aerial part extracts. Furthermore, the mechanisms of their anticonvulsant activities were also evaluated. Materials and Methods: Seizure was induced by Pentylen...

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Anticonvulsant effect of Satureja hortensis aerial parts extracts in mice

OBJECTIVE Regarding the anticonvulsant effects of Satureja hortensis (S . hortensis) in Avicenna's book: canon of medicine; the present study was undertaken to evaluate the anti- eplileptic effects of S . hortensis aqueous and ethanolic aerial part extracts. Furthermore, the mechanisms of their anticonvulsant activities were also evaluated. MATERIALS AND METHODS Seizure was induced by Pentyle...

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Aqueous extract of Berberis integerrima root improves renal dysfunction in streptozotocin induced diabetic rats

OBJECTIVE Barberry root extract contains various alkaloids that are considered as antioxidants. Beneficial effect of aqueous extract of Berberis integerrima root (AEBIR) was evaluated for renal function in diabetic rats induced by STZ. MATERIAL AND METHODS Diabetes was induced by i.p. injection of streptozotocin (65 mg/kg bw) to rats, after 15 h of fasting. Diabetic rats were randomly grouped...

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Protective effect of methanolic extract of Berberis integerrima Bunge. root on carbon tetrachloride-induced testicular injury in Wistar rats.

BACKGROUND Tissue protective effect of compounds with antioxidant properties has been demonstrated. The alkaloids found in barberry root are considered as antioxidants. OBJECTIVE According to barberry protective effects in different tissues, in this study, the protective effect of Berberis integerrima Bge. root )MEBIR) was evaluated against CCl4-induced testicular damages in Wistar rats. MA...

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عنوان ژورنال:
research in pharmaceutical sciences

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