validated stability indicating hplc method for the determination of mebeverine in the presence of its degradation products: kinetics study of its degradation in oxidative condition
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a stability indicating hplc method for determination of mebeverine in the presence of its degradation products and kinetic study of its degradation in oxidative condition
an hplc method for determination of mebeverine hydrochloride (mh) in the presence of its degradation products was developed. the degradation of mh was studied under hydrolysis, oxidative and photolysis stress conditions. under alkaline, acidic and oxidative conditions, degradation of mh was observed. the separation was performed using a symmetry c 18 column and a mixture of 50 mm kh 2 po 4 , ac...
متن کاملA stability indicating HPLC method for determination of mebeverine in the presence of its degradation products and kinetic study of its degradation in oxidative condition
An HPLC method for determination of mebeverine hydrochloride (MH) in the presence of its degradation products was developed. The degradation of MH was studied under hydrolysis, oxidative and photolysis stress conditions. Under alkaline, acidic and oxidative conditions, degradation of MH was observed. The separation was performed using a Symmetry C18 column and a mixture of 50 mM KH2PO4, acetoni...
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عنوان ژورنال:
research in pharmaceutical sciencesجلد ۷، شماره ۵، صفحات ۰-۰
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