protein bioconjugates: the novel delivery system for l-asparaginase

Novel delivery system for natural products: Nano-curcumin formulations

Objective: Curcumin is extracted from Curcuma longa and regulates the intracellular signal pathways which control the growth of cancerous cell, inflammation, invasion and apoptosis. Curcumin molecules have special intrinsic features that can target the intracellular enzymes, genome (DNA) and messengers (RNA). A wide range of studies have been conducted on the physicochemical traits and pharmaco...

cpps-proteins complexes as a novel topical protein delivery system

Aptamer-Nanoparticle Bioconjugates for Drug Delivery

Hyaluronic Acid Bioconjugates for the Delivery of Bioactive Molecules

Hyaluronic acid (HA) has currently several therapeutic applications: in ophthalmology, osteoarthritis, wound healing, tissue regeneration, postoperative anti-adhesion and anesthetic medicine. In the last ten years, it has also been successfully investigated in the field of drug delivery, in the form of conjugates or hydrogel depot systems. HAylation, the covalent conjugation of HA to bioactive ...

The molecular perspective: l-asparaginase.

The Oncologist 2005;10:238–239 www.TheOncologist.com Correspondence: David S. Goodsell, Ph.D., Associate Professor, The Scripps Research Institute, Department of Molecular Biology, 10550 North Torrey Pines Road, La Jolla, California 92037, USA. Telephone: 858-784-2839; Fax: 858-784-2860; e-mail: [email protected] Website: http://www.scripps.edu/pub/goodsell Received January 5, 2005; accepted...

Synthesis and Characterization of Novel Modified and Functionalized Silica Nano-particles for Protein Delivery Applications

In this study, the synthesis, characterization and controlled release behavior of new Hollow Silica Nano particles (HSNPs) and Magnetic Silica Nano Particles (MSNPs) were studied. Magnetic Silica Nano particles (MSNPs), as drug delivery vehicles, were synthesized through the coating of Fe3O4 nano-crystals with silica layers. The HSNPs were obtained by removal of Fe3O4 templates with hydrochlori...