protective effects of crocin on cardiotoxicity induced by subchronic adminstration of diazinon in rats
نویسندگان
چکیده
منابع مشابه
Protective effect of crocin on diazinon induced cardiotoxicity in rats in subchronic exposure.
UNLABELLED This study was designed to evaluate the effectiveness of crocin, main component of Crocus sativus L. (Saffron) against subchronic diazinon (DZN) induced cardiotoxicity in rats. METHODS Rats were divided into 7 groups; control (corn oil, gavage), DZN (15 mg/kg/day, gavage,), crocin (12.5, 25 or 50 mg/kg/day, i.p) plus DZN, vitamin E (200 IU/kg, i.p, three times per week) plus DZN an...
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Background: Increasing use of pesticides is one of the health hazards. Physical activity and medicinal plants appear to be a strategy to mitigate the adverse effects of these substances. Objective: The purpose of this study was to investigate the effect of resistance training and berberine chloride on apoptosis and oxidative stress markers in the heart tissue of diazinon-infected rats. Methods:...
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Objective(s): Gentamicin is used for the treatment of Gram-negative bacterial infections. However, gentamicin administration is limited because of nephrotoxicity. The aim of the present study was to evaluate the protective effect of crocin against gentamicin-induced nephrotoxicity in rats. Materials and Methods: Thirty two male Wistar rats received gentamicin (100 mg/kg, IP), with or without c...
متن کاملCrocin Restores Hypotensive Effect of Subchronic Administration of Diazinon in Rats
Objective(s): In this study, the effects of crocin against subchronic toxicity of diazinon (DZN) on systolic blood pressure (SBP) and heart rate (HR) were evaluated in rats. Materials and Methods: Rats were equally divided into 7 groups; control (corn oil), DZN (15 mg/kg), crocin (each group received 12.5, 25 or 50 mg/kg crocin plus DZN), vitamin E (200 IU/kg plus DZN) and crocin (50 mg/kg) tre...
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عنوان ژورنال:
research in pharmaceutical sciencesجلد ۷، شماره ۵، صفحات ۰-۰
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