renal function in children with febrile convulsions

how to cite this article: afsharkhas l, tavasoli a. renal function in children with febrile convulsions.iran j child neurol. 2014 autumn;8(4):57-61. abstract objective febrile convulsions (fc) are the most frequent seizure disorder in children. some studies have detected serum electrolyte disturbances in patients with fc. this study determines serum electrolytes, renal function tests, and frequency of urinary tract infection in hospitalized children with fc. materials & methods in this descriptive, cross sectional study, we evaluated 291 children with fc admitted to the neurology ward of ali-asghar children’s hospital from 2008–2013. data was recorded on age, sex, type (simple, complex), and recurrence of seizures, family history of fc and epilepsy, serum electrolytes, renal function tests, and urinary tract infections. results a total of 291 patients with diagnosis of fc were admitted to our center. of these 291 patients, 181 (62.2%) were male. the mean age was 24.4 ± 14.6 months. there were simple, complex, and recurrent fcs in 215 (73.9%), 76 (26.1%) and 61 (21%) of patients, respectively. urinary tract infections (uti) were found in 13 (4.5%) patients, more present in females (p-value = 0.03) and under 12 months of age (p-value = 0.003). hyponatremia, hypocalcemia, and hypokalemia was detected in 32 (11%), 16 (5.5%), and 4 (1.4%) of cases, respectively. twentyfour (8.2%) patients had a glomerular filtration rate less than 60 ml/min/1.73m2. there were no abnormalities in serum magnesium, bun, and creatinine levels. conclusion during fcs, mild changes may occur in renal function but a serum electrolyte evaluation is not necessary unless patients are dehydrated. in children with fc, urinary tract infections should be ruled out.   references ghofrani m. febrile convulsion: another look at an old subject. iran j child neurology 2006 june:1(1):5-9. swaiman k, ashwal s, ferriero d, schor n. swaiman’s pediatric neurology: principles and practice. 5 th edition.2012.pp.790-798. mohammadi m. febrile seizures: four steps algorithmic clinical approach. iranian journal of pediatrics 2010; 20(1):5-15. commission on epidemiology and prognosis, international league against epilepsy. guidelines for epidemiologic studies on epilepsy. epilepsia 1993;34(4):592–6. saghazadeh a, mastrangelo m, n. genetic background of febrile seizures. rev neurosci 2014;25(1):129-61. np. evaluation of the child who convulses with fever. pediatr 2003;5(7):457-61. karimzadeh p, fahimzad a, poormehdi ms. febrile convulsions: the role played by paraclinical evaluation. iran j child neurology 2008;2(4):21-24. kwong kl, tong ks, so kt. management of febrile convulsion: scene in a regional hospital. hong kong med j 2003 oct; 9(5):319-22. amiri m, farzin l, moassesi me, sajadi f. serum trace element levels in febrile convulsion. biol trace elem res 2010; 135(1-3):38-44. amouian s, mohammadian s, behnampour n tizrou m. trace elements in febrile seizure compared to febrile children admitted to an academic hospital in iran, 2011. journal of clinical and diagnostic research 2013 oct;7(10): 2231-2233. behrman e r. nelson textbook of pediatrics . in: bleyer a, ritchey a.k. nephrology section. 19th edition. 2011. p.1731-1845. momen a, monajemzadeh sm. the frequency of urinary tract infection among children with febrile convulsion. iranian journal of child neurology 2011: 1(1):29-31. sahib el-radhi a, carroll j, klein n. clinical manual of fever in children. springer. 2011. p.8-9. heydarian, f, ashrafzadeh f, kam s. simple febrile seizure: the role of serum sodium levels in prediction of seizure recurrence during the first 24 hours. iranian journal of child neurology 2009;3(2):31-34. nickavar a, hassanpour h, sotoudeh k. validity of serum sodium and calcium screening in children with febrile convulsion. acta medica iranica 2009;47(3):229-231. talebian a, vakili z, talar sa, kazemi sm, mousavi ga. assessment of the relation between serum zinc & magnesium levels in children with febrile convulsion. iran j pathol 2009; 4(4):157-160. teach sj, geil pa. incidence of bacteremia, urinary tract infection & unsuspected bacterial meningitis in children with febrile seizures. pediatric emergency care 1999; 15(1)9-12.