antinociceptive activity of trigonella foenum-graecum leaves and seeds (fabaceae)
نویسندگان
چکیده
present study reports analgesic activity of petroleum ether, chloroform, ethyl acetate and methanolic extracts of leaves and seeds of trigonella foenum-graecum linn. (fabaceae) using hot plate method for evaluation of central analgesic activity and acetic acid induced writhing test for evaluation of peripheral analgesic activity in mice. all the extracts of trigonella foenum-graecum showed significant central and peripheral analgesic activity at the dose of 50 mg/kg intraperitoneally. amongst all the extract methanolic extract of leaves of trigonella foenum-graecum showed highest increase in reaction time in hot plate method and more inhibitory effect on writhing induced by acetic acid. pentazocin and paracetamol was taken as standard drug for hot plate and writhing model respectively.
منابع مشابه
Antinociceptive Activity of Trigonella foenum-graecum Leaves and Seeds (Fabaceae)
Present study reports analgesic activity of petroleum ether, chloroform, ethyl acetate and methanolic extracts of leaves and seeds of Trigonella foenum-graecum Linn. (Fabaceae) using hot plate method for evaluation of central analgesic activity and acetic acid induced writhing test for evaluation of peripheral analgesic activity in mice. All the extracts of Trigonella foenum-graecum ...
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Petroleum ether, ethanol and water extracts of Trigonella foenum graecum seeds were investigated separately to determine their antiimplantation (antifertility) and estrogenic/antiestrogenic activity in female albino rats and Swiss mice. Among these, ethanol extract was found to be the most effective as antiimplantation and estrogenic agent. In preliminary phytochemical screening, ethanol extrac...
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This study was undertaken to examine the antioxidant activity of methanolic extract of seeds of Trigonella foenum-graecum seeds using DPPH free radical scavenging assay. The IC50 (The concentration of sample required to scavenge 50% of DPPH free radical) was calculated by plotting graph between % inhibition vs concentration. The Ascorbic acid was used as standard antioxidant in comparison to me...
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عنوان ژورنال:
iranian journal of pharmacology and therapeuticsجلد ۸، شماره ۲، صفحات ۵۷-۰
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